VIP (Vasoactive Intestinal Peptide) — 10mg

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the secretin/glucagon superfamily, widely distributed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune tissue. As one of the most pleiotropic signalling peptides identified, VIP has attracted broad research interest across neuroscience, immunology, pulmonary biology, and circadian rhythm regulation.

Mechanism of Interest
VIP exerts its effects by binding to two G-protein coupled receptors — VPAC1 and VPAC2 — which are expressed across a diverse range of tissues. Through these receptors, VIP modulates smooth muscle relaxation, vasodilation, glandular secretion, and immune cell activity. It is also a key neuropeptide in the suprachiasmatic nucleus (SCN), where it plays a critical role in coordinating circadian rhythm synchronisation between cells. Its potent anti-inflammatory properties have made it a subject of considerable interest in inflammatory and autoimmune disease modelling.

Research Focus Areas
• VPAC1 and VPAC2 receptor binding and downstream signalling
• Smooth muscle relaxation and vasodilation models
• Gastrointestinal motility and secretion research
• Neuroinflammation and anti-inflammatory signalling studies
• Circadian rhythm regulation and SCN biology
• Pulmonary vasodilation and airway biology research
• Immune modulation and autoimmune disease models
• Neuroprotective signalling pathways

Specifications
• Total content: 10mg
• Form: Lyophilised powder
• Purity: ≥99% — HPLC verified
• Storage: 2–8°C, away from light and moisture

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Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.