Tesamorelin — 10mg

Tesamorelin is a synthetic analogue of Growth Hormone Releasing Hormone (GHRH), consisting of the full 44-amino acid sequence of endogenous GHRH with a trans-3-hexenoic acid group conjugated to its N-terminus. This modification significantly enhances metabolic stability by protecting the peptide from degradation by dipeptidyl peptidase IV (DPP-IV), resulting in a longer-acting and more stable GHRH analogue compared to native GHRH — making it one of the most well-characterised GHRH analogues available for research.

Mechanism of Interest
Tesamorelin binds to and activates the GHRH receptor on pituitary somatotroph cells, stimulating endogenous growth hormone synthesis and pulsatile secretion. Unlike exogenous GH administration, Tesamorelin preserves the physiological feedback mechanisms of the GH axis — including somatostatin regulation — resulting in a more natural GH release pattern. This makes it a particularly relevant research tool for studying the GH/IGF-1 axis under conditions that closely reflect endogenous signalling dynamics.

Research Focus Areas
• GHRH receptor activation and pituitary somatotroph research
• Endogenous GH stimulation and IGF-1 axis modelling
• Visceral adipose tissue metabolism and lipid research
• GH/IGF-1 feedback regulation studies
• Metabolic syndrome and body composition models
• DPP-IV resistance and peptide stability research
• Comparative GHRH analogue activity studies

Specifications
• Total content: 10mg
• Form: Lyophilised powder
• Purity: ≥99% — HPLC verified
• Storage: 2–8°C, away from light and moisture

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Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.