Melanotan II — 10mg

Melanotan II is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) — a naturally occurring peptide that plays a central role in pigmentation, sexual function, and appetite regulation. As a non-selective melanocortin receptor agonist, Melanotan II activates multiple receptor subtypes (MC1R, MC3R, MC4R, MC5R), making it one of the broadest-acting compounds in the melanocortin research class and a highly versatile tool across several distinct research areas.

About Melanotan II
Where PT-141 selectively targets MC3R and MC4R in the CNS, Melanotan II activates a wider range of melanocortin receptors — including MC1R, which governs skin pigmentation. This broader receptor profile has made it a key research compound across three major areas: skin pigmentation biology, sexual arousal and CNS signalling, and appetite and energy homeostasis.

Key Benefits:
• Skin pigmentation research — acts on MC1R to stimulate melanin production in melanocytes, making it the primary compound studied for UV-independent pigmentation models
• Sexual function and arousal — MC4R activation in the hypothalamus is studied for CNS-mediated arousal signalling, similar to but broader than PT-141
• Appetite suppression — MC3R and MC4R activity in the hypothalamus is researched for its role in reducing food intake and regulating energy balance
• Broad melanocortin receptor coverage — activates MC1R, MC3R, MC4R and MC5R simultaneously for multi-pathway research
• UV protection biology — pigmentation research includes studying melanin’s role as a natural photoprotective mechanism
• Sebaceous gland research — MC5R activation opens up research into skin oil production and sebaceous biology
• Versatile comparator compound — its broad receptor profile makes it ideal for comparing against selective agonists like PT-141 and alpha-MSH

Research Focus Areas
• Melanocortin receptor (MC1R / MC3R / MC4R / MC5R) binding studies
• Melanin synthesis and UV-independent pigmentation models
• Hypothalamic appetite and energy homeostasis research
• CNS-mediated sexual arousal and motivation pathways
• Photoprotection and UV response biology
• Sebaceous gland function and skin biology
• Comparative melanocortin agonist research

Specifications
• Total content: 10mg
• Form: Lyophilised powder
• Purity: ≥99% — HPLC verified
• Storage: 2–8°C, away from light and moisture

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Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.