Tamoxifen — 40 x 20mg Tablets

Tamoxifen is a selective estrogen receptor modulator (SERM) and one of the most extensively studied compounds in endocrine and oncology research. As a non-steroidal triphenylethylene derivative, Tamoxifen exhibits tissue-selective estrogen receptor activity — acting as an estrogen antagonist in some tissues while functioning as a partial agonist in others. This tissue-selective profile has made it a foundational research tool in estrogen receptor biology, hormonal signalling, and breast tissue research for decades.

Mechanism of Interest
Tamoxifen competitively binds to estrogen receptors (ERα and ERβ), blocking estrogen from binding and triggering downstream transcriptional activity in receptor-positive cell models. Its active metabolite, 4-hydroxytamoxifen, binds the estrogen receptor with significantly higher affinity than the parent compound and is a key subject in receptor binding and pharmacokinetic research. The tissue-selective nature of its agonist/antagonist activity — antagonist in breast tissue, partial agonist in bone and uterine tissue — makes it an invaluable tool for studying context-dependent estrogen receptor signalling.

Research Focus Areas
• Estrogen receptor (ERα / ERβ) binding and signalling studies
• Selective estrogen receptor modulator (SERM) activity research
• Hormone-receptor positive cell line research models
• 4-hydroxytamoxifen metabolite and pharmacokinetic studies
• Bone metabolism and estrogen receptor agonism models
• HPG axis and sex hormone feedback research
• Anti-proliferative signalling pathway studies

Specifications
• Quantity: 40 tablets x 20mg per tablet (800mg total)
• Form: Oral tablet
• Active ingredient: Tamoxifen citrate
• Storage: Store at room temperature, away from light and moisture

———

Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.