MGF (Mechano Growth Factor) — 2mg

Mechano Growth Factor (MGF) is a splice variant of Insulin-like Growth Factor 1 (IGF-1), produced locally in tissue in response to mechanical stress or damage. Unlike systemic IGF-1, MGF acts in a highly localised manner, making it a distinct and valuable research tool for studying the early-phase cellular response to tissue loading and injury — particularly in skeletal muscle and connective tissue models.

Mechanism of Interest
MGF is generated when the IGF-1 gene undergoes alternative splicing following mechanical stimulation. Its unique C-terminal peptide sequence differentiates it from IGF-1Ea and other splice variants, and is believed to be responsible for activating satellite cells (muscle stem cells) and initiating local tissue repair signalling. This localised, stimulus-dependent activity makes MGF a key subject in mechanobiology and tissue regeneration research.

Research Focus Areas
• IGF-1 splice variant and mechanobiology studies
• Satellite cell activation and muscle stem cell research
• Localised tissue repair and remodelling models
• Skeletal muscle hypertrophy signalling pathways
• Connective tissue and tendon stress-response research
• Comparative IGF-1 variant activity studies

Specifications
• Total content: 2mg
• Form: Lyophilised powder
• Purity: ≥99% — HPLC verified
• Storage: 2–8°C, away from light and moisture

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Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.