TB-500 (Thymosin Beta-4 Fragment) — 10mg

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein present in virtually all human and animal cells. Corresponding to the actin-binding domain of Thymosin Beta-4, TB-500 retains the core biological activity of the full-length protein while offering improved research utility as a shorter, more stable synthetic fragment. It is one of the most widely studied peptides in systemic tissue repair and regeneration research.

Mechanism of Interest
TB-500’s primary mechanism of research interest lies in its interaction with G-actin — sequestering actin monomers and regulating actin polymerisation dynamics critical to cell motility and migration. By promoting cell migration and proliferation, TB-500 facilitates the movement of repair cells to sites of tissue interest. It also upregulates the expression of various growth factors and cytokines involved in angiogenesis and extracellular matrix remodelling, and exhibits notable anti-inflammatory properties across multiple research models.

Research Focus Areas
• Actin-binding and cell motility studies
• Systemic cell migration and recruitment modelling
• Angiogenesis and vascular remodelling research
• Anti-inflammatory signalling and cytokine modulation
• Connective tissue and extracellular matrix studies
• Musculoskeletal repair and recovery models
• Cardiac and smooth muscle tissue research
• Wound healing and dermal repair biology

Specifications
• Total content: 10mg
• Form: Lyophilised powder
• Purity: ≥99% — HPLC verified
• Storage: 2–8°C, away from light and moisture

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Important Notice

This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use.

By purchasing, the buyer confirms they are a qualified professional or acting on behalf of a licensed research facility and accept full responsibility for safe handling, storage, and use in accordance with all applicable guidelines. No claims are made regarding the safety or effectiveness of this compound outside of a controlled research environment.